Peer Reviewed Publications
- Polis B., Gurevich V., Assa M., Samson A.O.,
"Norvaline Restores the BBB Integrity in a Mouse Model of Alzheimer's Disease",
2019, International Journal of Molecular Sciences. 18;20(18).
PubMed
- Atrahimovich D., Samson A.O., Barsheshet Y., Vaya J., Khatib S., Reuveni E.
"Genome-wide localization of the polyphenol quercetin in human monocytes",
2019, BMC Genomics. 20(1):606.
PubMed
- Meirson T., Bomze D., Kahlon L., Gil-Henn H., Samson A.O.
"A helical lock and key model of polyproline II conformation with SH3",
2019, Bioinformatics.
PubMed
- Polis B., Srikanth K.D., Gurevich V., Gil-Henn H., Samson A.O.
"L-Norvaline, a new therapeutic agent against Alzheimer's disease",
2019, Neural Regeneration Research. 14(9):1562-1572.
PubMed
- Polis B., Samson A.O.
"Arginase as a Potential Target in the Treatment of Alzheimer's Disease",
2018, Advances in Alzheimer's Disease. 7(4), 119-140.
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Fonar G., Polis B., Meirson T., Maltsev A., Samson A.O.
"Subcutaneous Sustained-Release of Poly-Arginine Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease",
2018, Advances in Alzheimer's Disease. 7(4), 153-182.
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Polis B., Srikanth K.D., Elliott E., Gil-Henn H., Samson A.O.
"L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease.",
2018, Neurotherapeutics. 15(4):1036-1054.
PubMed
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Atrahimovich D, Samson A.O., Khattib A., Vaya J., Khatib S.
"Punicalagin Decreases Serum Glucose Levels and Increases PON1 Activity and HDL Anti-Inflammatory Values in Balb/c Mice Fed a High-Fat Diet",
2018, Oxid Med Cell Longev. 2018:2673076.
PubMed
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Fonar G., Polis B., Meirson T., Maltsev A., Elliott E., Samson A.O.
"Intracerebroventricular Administration of L-arginine Improves Spatial Memory Acquisition in Triple Transgenic Mice Via Reduction of Oxidative Stress and Apoptosis.",
2018, Translational Neuroscience. 9:43-53.
PubMed
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Meirson T., Genna A., Lukic N., Makhnii T., Alter J., Sharma V.P., Wang Y., Samson A.O., Condeelis J.S., Gil-Henn H.
"Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors.",
2018, Oncotarget. 9(31):22158-22183.
PubMed
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Zattelman L., Regev R., Usaj M., Reinke P.Y.A., Giese S., Samson A. O., Taft M.H., Manstein D.J., Henn A.
"N-terminal splicing extensions of the human MYO1C gene fine-tune the kinetics of the three full-length myosin IC isoforms.",
2017, Journal of Biological Chemistry. 292(43):17804-17818.
PubMed
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Glantz-Gashai Y., Meirson T., Reuveni E., Samson A. O.
"Virtual screening for potential inhibitors of Mcl-1 conformations sampled by normal modes, molecular dynamics, and nuclear magnetic resonance.",
2017, Drug Design Development and Therapy. 11:1803-1813.
PubMed
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Meirson T., Samson A. O., Gil-Henn H.
"An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.",
2017, Drug Design Development and Therapy. 11:1535-1557.
PubMed
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Aran A., Segel R., Kaneshige K., Gulsuner S., Renbaum P., Oliphant S., Meirson T., Weinberg-Shukron A., Hershkovitz Y., Zeligson S., Lee M.K., Samson A. O., Parsons S.M., King M.C., Levy-Lahad E., Walsh T.
"Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome", 2017, Neurology. 88:1021-1028.
PubMed
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Falik Zaccai T.C., Savitzki D., Zivony-Elboum Y., Vilboux T., Fitts E.C., Shoval Y., Kalfon L., Samra N., Keren Z., Gross B., Chasnyk N., Straussberg R., Mullikin J.C., Teer J.K., Geiger D., Kornitzer D., Bitterman-Deutsch O., Samson A. O., Wakamiya M., Peterson J.W., Kirtley M.L., Pinchuk I.V., Baze W.B., Gahl W.A., Kleta R., Anikster Y., Chopra A.K.
"Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy."
2017, Brain. 140:370-386.
PubMed
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Glantz-Gashai Y., Meirson T., and Samson A. O.
"Normal Modes Expose Active Sites in Enzymes",
2016, PLoS Comput Biol. 21,12.
PubMed
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Dabour R., Meirson T., and Samson A. O.
"Global antibiotic resistance is mostly periodic"
2016, J Glob Antimicrob Resist. 7:132-134.
PubMed
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Atrahimovich D., Khatib S., Sela S., Vaya J., and Samson A. O.
"Punicalagin Induces Serum Low-Density Lipoprotein Influx to Macrophages"
2016, Oxid Med Cell Longev. 2016:71242-51.
PubMed
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Reuveni E., Samson A. O., and Giuliani A.,
"Principal component analysis of mouse genomes unravels strong genetic robustness during evolution"
2015, International J of Medical Biotech and Genetics. 1:1-6.
PubMed
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Weinberg-Shukron A., Renbaum P., Kalifa R., Zeligson S., Ben-Neriah Z., Dreifuss A., Abu-Rayyan A., Maatuk N, Fardian N, Rekler D, Kanaan M, Samson A.O., Levy-Lahad E, Gerlitz O, and Zangen D.
"A mutation in the nucleoporin-107 gene causes XX gonadal dysgenesis" ,
2015, The Journal of Clinical Investigation. 125:4295-304.
PubMed
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Fonar G., and Samson A. O.
"NMR structure of the water soluble Aβ17-34 peptide",
2014, Bioscience Reports. Pubmed
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Maatuk N., Glantz-Gashai Y., Rotman M., Baydany M., Fonar G., Shechvitz A., Shemer K., Peleg A., Reuveni E., and Samson A. O.
"PHI-DAC: protein homology database through dihedral angle conservation",
2014, Bioinformatics. PubMed
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Greenberger M. M., and Samson A. O.
"Normal mode dynamics of voltage-gated K+ channels: gating principle, opening mechanism, and inhibition" ,
2014, Journal of Computational Neuroscience.
PubMed
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Kolan D., Fonar G., and Samson A. O..
"Elastic network normal modes reveal the GPCR activation mechanism",
2013, Protein: Structure, Function, and Bioinformatics.
PubMed
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Kolodny R., Pereyeslavets L., Samson A. O., and Levitt M.
"On the universe of protein folds",
2013, Annual Review of Biophysics, 42, 559-582.
PubMed
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Maatuk N., and Samson A. O.
"Modeling the binding mechanism of Alzheimer's Aβ(1-42) to nicotinic acetylcholine receptors based on similarity with snake α-neurotoxins.",
2012, Neurotoxicology, 50, 2243-8.
PubMed
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Samson A. O., and Levitt M.,
"Normal modes of prion proteins: from native to infectious particle",
2011, Biochemistry, 50, 2243-8.
PubMed
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Samson A. O., and Levitt M.,
" Protein segment finder: an online search engine for segment motifs in the PDB",
2009, Nucleic Acid Research, 37 (Database issue), D224-8.
PubMed
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Samson A. O., and Levitt M.,
"Inhibition mechanism of the acetylcholine receptor by α-neurotoxins as revealed by normal mode dynamics",
2008, Biochemistry, 47, 4065-4070.
PubMed
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Rosen O., Samson A.O., and Anglister J.,
"Correlated mutations at gp120 positions 322 and 440: implications for gp120 structure",
2008, Proteins, 71, 1066-70.
PubMed
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Rosen O., Samson A. O., Sharon M., Zolla-Pazner S., and Anglister J.,
"Response to Matters Arising ",
2006, Structure, 14, 649-651.
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Samson A. O., and Anglister J.,
"2D-measurement of proton T1π relaxation in unlabeled proteins: α-bungarotoxin complex with acetylcholine receptor peptide",
2005, Biochemistry, 44, 10926-10934.
PubMed
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Biron Z., Khare S., Samson A.O., Naider F., and Anglister J.
"A monomeric 310-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41" ,
2002, Biochemistry, 41, 12687-12696.
PubMed
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Yassin L., Samson A.O., Halevi S., Eshel M., and Treinin M.,
"Mutations in the extracellular domain and in the membrane spanning domains interfere with nicotinic acetylcholine receptor maturation",
2002, Biochemistry, 41, 12329-12335.
PubMed
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Samson A.O., Scherf. T., Eisenstein M., Chill J., and Anglister J.,
"The mechanism for acetylcholine receptor inhibition by α-neurotoxins and species-specific resistance to α-bungarotoxin revealed by NMR",
2002, Neuron, 35, 319-332.
Pubmed
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Yao Y., Wang J., Viroonchatapan N., Rothe E., Samson A.O., Chill J., Anglister J., and Wang Z.
"Yeast expression and NMR analysis of the extracellular domain of muscle nicotinic acetylcholine receptor α-subunit",
2002, Journal of Biological Chemistry, 277(15), 12613-12621.
Pubmed
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Samson A.O., Chill J., Rodriguez E., Scherf T., and Anglister J.,
"NMR mapping and secondary structure determination of the major acetylcholine receptor α-subunit determinant interacting with α-bungarotoxin",
2001, Biochemistry, 40, 5464-5473.
Pubmed
Books
· Polis B., Samson A.O. "Arginase as a potential target in the treatment of Alzheimer's disease" (2018) Lambert academic publishing.
Book chapters
· Samson A. O., Scherf T., Eisenstein M., Chill J. H., and Anglister J., "The mechanism for acetylcholine receptor inhibition by α-neurotoxins and species specific resistance to α-bungarotoxin revealed by NMR" (2004) Cholinergic mechanisms, function and dysfunction, p.45-54, Taylor & Francis group, UK.
· Samson A. O., Scherf T., Eisenstein M., and Anglister J., "Interactions of toxins with cholinergic proteins", (2004) Cholinesterases in the second millenium: Biomolecular and Pathological Aspects, p.285-93, Diseסo e Impresiones Ltda. press. Pucon, Chile.