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Peer Reviewed Publications

  1. Polis B., Gurevich V., Assa M., Samson A.O., "Norvaline Restores the BBB Integrity in a Mouse Model of Alzheimer's Disease", 2019, International Journal of Molecular Sciences. 18;20(18). PubMed

  2. Atrahimovich D., Samson A.O., Barsheshet Y., Vaya J., Khatib S., Reuveni E. "Genome-wide localization of the polyphenol quercetin in human monocytes", 2019, BMC Genomics. 20(1):606. PubMed

  3. Meirson T., Bomze D., Kahlon L., Gil-Henn H., Samson A.O. "A helical lock and key model of polyproline II conformation with SH3", 2019, Bioinformatics. PubMed

  4. Polis B., Srikanth K.D., Gurevich V., Gil-Henn H., Samson A.O. "L-Norvaline, a new therapeutic agent against Alzheimer's disease", 2019, Neural Regeneration Research. 14(9):1562-1572. PubMed

  5. Polis B., Samson A.O. "Arginase as a Potential Target in the Treatment of Alzheimer's Disease", 2018, Advances in Alzheimer's Disease. 7(4), 119-140.

  6. Fonar G., Polis B., Meirson T., Maltsev A., Samson A.O. "Subcutaneous Sustained-Release of Poly-Arginine Ameliorates Cognitive Impairment in a Transgenic Mouse Model of Alzheimer's Disease", 2018, Advances in Alzheimer's Disease. 7(4), 153-182.

  7. Polis B., Srikanth K.D., Elliott E., Gil-Henn H., Samson A.O. "L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease.", 2018, Neurotherapeutics. 15(4):1036-1054. PubMed

  8. Atrahimovich D, Samson A.O., Khattib A., Vaya J., Khatib S. "Punicalagin Decreases Serum Glucose Levels and Increases PON1 Activity and HDL Anti-Inflammatory Values in Balb/c Mice Fed a High-Fat Diet", 2018, Oxid Med Cell Longev. 2018:2673076. PubMed

  9. Fonar G., Polis B., Meirson T., Maltsev A., Elliott E., Samson A.O. "Intracerebroventricular Administration of L-arginine Improves Spatial Memory Acquisition in Triple Transgenic Mice Via Reduction of Oxidative Stress and Apoptosis.", 2018, Translational Neuroscience. 9:43-53. PubMed

  10. Meirson T., Genna A., Lukic N., Makhnii T., Alter J., Sharma V.P., Wang Y., Samson A.O., Condeelis J.S., Gil-Henn H. "Targeting invadopodia-mediated breast cancer metastasis by using ABL kinase inhibitors.", 2018, Oncotarget. 9(31):22158-22183. PubMed

  11. Zattelman L., Regev R., Usaj M., Reinke P.Y.A., Giese S., Samson A. O., Taft M.H., Manstein D.J., Henn A. "N-terminal splicing extensions of the human MYO1C gene fine-tune the kinetics of the three full-length myosin IC isoforms.", 2017, Journal of Biological Chemistry. 292(43):17804-17818. PubMed

  12. Glantz-Gashai Y., Meirson T., Reuveni E., Samson A. O. "Virtual screening for potential inhibitors of Mcl-1 conformations sampled by normal modes, molecular dynamics, and nuclear magnetic resonance.", 2017, Drug Design Development and Therapy. 11:1803-1813. PubMed

  13. Meirson T., Samson A. O., Gil-Henn H. "An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.", 2017, Drug Design Development and Therapy. 11:1535-1557. PubMed

  14. Aran A., Segel R., Kaneshige K., Gulsuner S., Renbaum P., Oliphant S., Meirson T., Weinberg-Shukron A., Hershkovitz Y., Zeligson S., Lee M.K., Samson A. O., Parsons S.M., King M.C., Levy-Lahad E., Walsh T. "Vesicular acetylcholine transporter defect underlies devastating congenital myasthenia syndrome", 2017, Neurology. 88:1021-1028. PubMed

  15. Falik Zaccai T.C., Savitzki D., Zivony-Elboum Y., Vilboux T., Fitts E.C., Shoval Y., Kalfon L., Samra N., Keren Z., Gross B., Chasnyk N., Straussberg R., Mullikin J.C., Teer J.K., Geiger D., Kornitzer D., Bitterman-Deutsch O., Samson A. O., Wakamiya M., Peterson J.W., Kirtley M.L., Pinchuk I.V., Baze W.B., Gahl W.A., Kleta R., Anikster Y., Chopra A.K. "Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy." 2017, Brain. 140:370-386. PubMed

  16. Glantz-Gashai Y., Meirson T., and Samson A. O. "Normal Modes Expose Active Sites in Enzymes", 2016, PLoS Comput Biol. 21,12. PubMed

  17. Dabour R., Meirson T., and Samson A. O. "Global antibiotic resistance is mostly periodic" 2016, J Glob Antimicrob Resist. 7:132-134. PubMed

  18. Atrahimovich D., Khatib S., Sela S., Vaya J., and Samson A. O. "Punicalagin Induces Serum Low-Density Lipoprotein Influx to Macrophages" 2016, Oxid Med Cell Longev. 2016:71242-51. PubMed

  19. Reuveni E., Samson A. O., and Giuliani A., "Principal component analysis of mouse genomes unravels strong genetic robustness during evolution" 2015, International J of Medical Biotech and Genetics. 1:1-6. PubMed

  20. Weinberg-Shukron A., Renbaum P., Kalifa R., Zeligson S., Ben-Neriah Z., Dreifuss A., Abu-Rayyan A., Maatuk N, Fardian N, Rekler D, Kanaan M, Samson A.O., Levy-Lahad E, Gerlitz O, and Zangen D. "A mutation in the nucleoporin-107 gene causes XX gonadal dysgenesis" , 2015, The Journal of Clinical Investigation. 125:4295-304. PubMed

  21. Fonar G., and Samson A. O. "NMR structure of the water soluble Aβ17-34 peptide", 2014, Bioscience Reports. Pubmed

  22. Maatuk N., Glantz-Gashai Y., Rotman M., Baydany M., Fonar G., Shechvitz A., Shemer K., Peleg A., Reuveni E., and Samson A. O. "PHI-DAC: protein homology database through dihedral angle conservation", 2014, Bioinformatics. PubMed

  23. Greenberger M. M., and Samson A. O. "Normal mode dynamics of voltage-gated K+ channels: gating principle, opening mechanism, and inhibition" , 2014, Journal of Computational Neuroscience. PubMed

  24. Kolan D., Fonar G., and Samson A. O.. "Elastic network normal modes reveal the GPCR activation mechanism", 2013, Protein: Structure, Function, and Bioinformatics. PubMed

  25. Kolodny R., Pereyeslavets L., Samson A. O., and Levitt M. "On the universe of protein folds", 2013, Annual Review of Biophysics, 42, 559-582. PubMed

  26. Maatuk N., and Samson A. O. "Modeling the binding mechanism of Alzheimer's Aβ(1-42) to nicotinic acetylcholine receptors based on similarity with snake α-neurotoxins.", 2012, Neurotoxicology, 50, 2243-8. PubMed

  27. Samson A. O., and Levitt M., "Normal modes of prion proteins: from native to infectious particle", 2011, Biochemistry, 50, 2243-8. PubMed

  28. Samson A. O., and Levitt M., " Protein segment finder: an online search engine for segment motifs in the PDB", 2009, Nucleic Acid Research, 37 (Database issue), D224-8. PubMed

  29. Samson A. O., and Levitt M., "Inhibition mechanism of the acetylcholine receptor by α-neurotoxins as revealed by normal mode dynamics", 2008, Biochemistry, 47, 4065-4070. PubMed

  30. Rosen O., Samson A.O., and Anglister J., "Correlated mutations at gp120 positions 322 and 440: implications for gp120 structure", 2008, Proteins, 71, 1066-70. PubMed

  31. Rosen O., Samson A. O., Sharon M., Zolla-Pazner S., and Anglister J., "Response to Matters Arising ", 2006, Structure, 14, 649-651.

  32. Samson A. O., and Anglister J., "2D-measurement of proton T relaxation in unlabeled proteins: α-bungarotoxin complex with acetylcholine receptor peptide", 2005, Biochemistry, 44, 10926-10934. PubMed

  33. Biron Z., Khare S., Samson A.O., Naider F., and Anglister J. "A monomeric 310-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41" , 2002, Biochemistry, 41, 12687-12696. PubMed

  34. Yassin L., Samson A.O., Halevi S., Eshel M., and Treinin M., "Mutations in the extracellular domain and in the membrane spanning domains interfere with nicotinic acetylcholine receptor maturation", 2002, Biochemistry, 41, 12329-12335. PubMed

  35. Samson A.O., Scherf. T., Eisenstein M., Chill J., and Anglister J., "The mechanism for acetylcholine receptor inhibition by α-neurotoxins and species-specific resistance to α-bungarotoxin revealed by NMR", 2002, Neuron, 35, 319-332. Pubmed

  36. Yao Y., Wang J., Viroonchatapan N., Rothe E., Samson A.O., Chill J., Anglister J., and Wang Z. "Yeast expression and NMR analysis of the extracellular domain of muscle nicotinic acetylcholine receptor α-subunit", 2002, Journal of Biological Chemistry, 277(15), 12613-12621. Pubmed

  37. Samson A.O., Chill J., Rodriguez E., Scherf T., and Anglister J., "NMR mapping and secondary structure determination of the major acetylcholine receptor α-subunit determinant interacting with α-bungarotoxin", 2001, Biochemistry, 40, 5464-5473. Pubmed

Books


· Polis B., Samson A.O. "Arginase as a potential target in the treatment of Alzheimer's disease" (2018) Lambert academic publishing.

Book chapters


· Samson A. O., Scherf T., Eisenstein M., Chill J. H., and Anglister J., "The mechanism for acetylcholine receptor inhibition by α-neurotoxins and species specific resistance to α-bungarotoxin revealed by NMR" (2004) Cholinergic mechanisms, function and dysfunction, p.45-54, Taylor & Francis group, UK.

· Samson A. O., Scherf T., Eisenstein M., and Anglister J., "Interactions of toxins with cholinergic proteins", (2004) Cholinesterases in the second millenium: Biomolecular and Pathological Aspects, p.285-93, Diseסo e Impresiones Ltda. press. Pucon, Chile.